MetaboNews January: María Eugenia Monge

Dr. María Eugenia Monge is an Independent Researcher of the National Scientific and Technical Research Council of Argentina (CONICET) and works at the Centro de Investigaciones en Bionanociencias (CIBION). In 2006, she earned her Ph.D. in analytical and physical chemistry from the University of Buenos Aires. Between 2007 and 2014, she held postdoctoral positions in Italy, France, and the USA.

In 2014, she was recruited by CONICET to set up a new laboratory in CIBION, which was a new research center in Argentina, where she leads the Bioanalytical Mass Spectrometry Group and the Mass Spectrometry facility. Her research group develops MS-based metabolomics and lipidomics analytical methods with applications in health and the environment. As well, her group contributes with pipelines for preprocessing LC-MS data for quality control procedures in untargeted workflows.

Some of the most exciting aspects of my work in metabolomics include being the mentor of an interdisciplinary group, and training students and postdocs with no previous knowledge in mass spectrometry or metabolomics, but with a solid background in analytical chemistry, biochemistry, biology, or computing science. This gives me the possibility of sharing my passion for science, and my belief that MS-based technologies can be transformative for disease diagnosis and contribute to global health equity.

María Monge

From her standpoint, technological advancements in metabolomics haven’t been uniformly shared on a global scale. Since her return to Argentina in 2014, she has been actively involved in organizing and teaching metabolomics courses for South American students. Additionally, she has played a role in advocating for the understanding and benefits of metabolomics across various Latin American countries, with the goal of expanding and reinforcing the South American community. Aligned with this mission, she is honored to serve as a Founding Member of the Latin American Metabolic Profiling Society (LAMPS), established in 2020. LAMPS is a nascent network committed to enhancing collaborations across the continent and promoting emerging technologies and practices that contribute to making science more reproducible and open.

As mentioned by most scientists, one of the greatest barriers in metabolomics studies is the complexity of data analysis and interpretation. Metabolomics data often involves a vast amount of information, requiring sophisticated tools and expertise to extract meaningful insights. MetaboAnalyst serves as a powerful solution to overcome this hurdle.

MetaboAnalyst is a comprehensive, Web-based tool designed for processing, analyzing, and interpreting metabolomic data. It handles most of the common metabolomic data types including compound concentration lists, spectral bin lists, peak lists, and raw MS spectra.

In addition to many feature enhancements, the version 6.0 contains three new modules – tandem MS spectral processing and compound annotation, dose response analysis for chemical risk assessment, and leveraging metabolite-genome wide association analysis and Mendelian randomization for causal analysis.

TMIC offers comprehensive advice and guidance on leveraging MetaboAnalyst for both targeted and untargeted metabolomics data analysis. We assist researchers in navigating the intricacies of the software, offering personalized support to ensure optimal utilization. By leveraging our expertise, users can streamline their metabolomics studies, unravel complex patterns, and uncover significant biological information.

Additionally, our service goes beyond just metabolomics by helping users integrate this data with other omics datasets, such as transcriptome and microbiome. This holistic approach enhances the depth and breadth of analysis, enabling researchers to gain a more comprehensive understanding of biological systems.

Contact us to gain invaluable insights and make informed decisions with our tailored support, provided directly by the developer of MetaboAnalyst.

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