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The Metabolomics Innovation Centre
  • Home
  • Services
    • Quantitative
    • Semi-Quantitative
    • Custom Services
  • Software
    • Databases
    • Web Servers & Data Analysis
  • Science
    • Publications
    • Research Hotel
    • Workshops
    • Video Resources
    • MetaboNews
  • About Us
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    • Equipment
    • ISAC
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    • Careers
    • News
  • Contact Us
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Global (Untargeted) Lipidomics Profiling

Quantitative Metabolomics
Lipidomics
Contact Us For More Details For More Details and To Order
Price
Academic
$203 per sample for 20 samples or more; Add $400 for 19 samples or less. Plus $600 flat fee for lipid identification per project and $200 flat fee for sample handling per project.
Industry
add 30% overhead
Minimum Volume

See List

Instrument
Description

We use a cutting-edge method to analyze the lipidome in both positive and negative ionization. It typically detects, identifies and relatively quantifies more than 5,000 lipids for positive ionization and more than 2,000 lipids for negative ionization. Deuterated internal lipid standards belonging to 15 different lipid classes are used for data normalization, providing accurate relative quantification. We also provide MS/MS analysis for the identification of the detected lipids. Approximately 1,000 lipids can be typically identified by MS/MS, while 3000 to 5000 lipids can be putatively identified by accurate mass-match. TMIC provides all sample preparation, lipid extraction, LC-MS analysis, data analysis, lipid identification, data normalization and statistical analysis (PCA, PLS-DA, Volcano plots). We will provide a summary of our analysis and statistical results. The detected lipids, putative identifications (MS/MS spectral match or accurate mass match) and their relative quantification data will be summarized in an Excel file, which can be used for further analysis such as uploading to MetaboAnalyst for more statistical analysis or pathway analysis.  

Platform Strengths

The incorporation of deuterated lipid standards allows for accurate, relative quantification for comparisons between samples. MS/MS provides high-confidence lipid identification.  

 

Quantitative

Includes 15 deuterated internal standards to provide accurate, relative quantification of different lipid classes.  

 

Metabolite Identification

Tier 1 – Identification requires mass error ≤5.0 mDa and MS/MS match score ≥500 when compared to published databases. Typically 150-900 lipids can be identified. Tier 2 – Identification requires mass error ≤5.0 mDa, MS/MS match score ≥500 and isotope pattern match score (mSigma) ≤100 when compared to published databases. Typically 100-500 lipids can be identified. Tier 3 – Putative identification based on MS data (i.e. m/z) matched to database hit. Typically 3000+ lipids can be identified.  

 

Statistical Analysis

Included.  

 

Price

Academic/Government: $203 per sample for 20 samples or more

Add $400 extra for 19 samples or less.

Plus a flat fee for lipid identification per project: $600

Plus a flat fee for sample handling per project: $200

 

Industry: add 30% overhead

We request that any publications, posters, or oral presentations resulting from work performed by The Metabolomics Innovation Centre acknowledge TMIC. This allows the Centre to report information such as impact on Canadian researchers to our funding agencies. Clients should also keep us apprised of any publications, posters, or oral presentations arising from work performed at TMIC.

Cutting edge services for metabolomics analysis, including targeted/quantitative analyses, global metabolomic analyses, and bioinformatics support.
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