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The Metabolomics Innovation Centre
  • Home
  • Services
    • Quantitative
    • Semi-Quantitative
    • Custom Services
  • Software
    • Databases
    • Web Servers & Data Analysis
  • Science
    • Publications
    • Research Hotel
    • Workshops
    • Video Resources
    • MetaboNews
  • About Us
    • People
    • Equipment
    • ISAC
    • Governance
    • Careers
    • News
  • Contact Us
  • LIMS (login)

Microbiome Metabolite Assay (MMA)

Quantitative Metabolomics
Contact Us For More Details For More Details and To Order
Price
Academic
$220/sample for 20 samples or more; Add $800 extra for 19 samples or less.
Industry
$286/sample for 20 samples or more; Add $800 extra for 19 samples or less.
Minimum Volume
Serum/Plasma: 50-150 μL
Urine: 25-50 μL
Saliva: 50-150 μL
Tissue: 10-40 mg
Feces: 10-40 mg
Microbes: 10-40 mg
Smaller amounts and Other types: Please inquire
Instrument
Description

Accurate relative quantification of 851 microbiome metabolites in comparative samples, including known microbiota-related metabolites (short-chain and medium-chain fatty acids, bile acids, nucleosides, benzoates and uremic compounds, tryptophan metabolism, tyrosine metabolism, phenylalanine metabolism, vitamins and derivatives, polyamines, neurotransmitters) and other microbiota-host-related endogenous metabolites (amino acid derivatives, glycolysis, TCA cycle and other energy metabolism, amino acid metabolisms).  

Quantitative

Accurate relative quantification with isotope standards for all individual metabolites using differential chemical isotope labeling of samples and UPLC-High Resolution MS.

Platform Strengths

  • High-coverage of microbiome metabolites
  • Accurate relative quantification using isotopic-assisted LC-MS
  • Sample normalization based on total metabolite concentrations measured in all individual samples
  • Minimum requirement: just send us the unprocessed raw samples and we will do the rest
  • Detailed report on experiments, quality assurance and quality control, metabolite IDs, quantification results, and statistical analysis

Metabolite Identification (Tier 1, Tier 2, Tier 3)

Metabolite identification is based on Tier 1 and Tier 2 criteria, including CIL Library based on accurate mass, RT and peak pairs.  

Statistical Analysis

Basic statistical analysis included.

Compounds

Metabolites

  • MMA Assay Compound List for Human Serum or Plasma

We request that any publications, posters, or oral presentations resulting from work performed by The Metabolomics Innovation Centre acknowledge TMIC. This allows the Centre to report information such as impact on Canadian researchers to our funding agencies. Clients should also keep us apprised of any publications, posters, or oral presentations arising from work performed at TMIC.

Cutting edge services for metabolomics analysis, including targeted/quantitative analyses, global metabolomic analyses, and bioinformatics support.
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