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The Metabolomics Innovation Centre
  • Home
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    • Semi-Quantitative
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    • Web Servers & Data Analysis
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    • Publications
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Purine/pyrimidine Synthesis Pathway

Quantitative Metabolomics

Absolute and Relative Quantitation

Quantitation of purine/pyrimidine synthesis and salvage metabolites using a combined LC-MRM/MS and high-resolution LC-MS approach for absolute (with internal standards) and relative quantitation.

Contact Us For More Details For More Details and To Order
Price
Academic
$400 1st sample; $120 each additional sample
Industry
$800 1st sample; $240 each additional sample
Minimum Volume

Tissue: 20 mg
Cell: 5×10^6
Blood/plasma/serum: TBD
Urine: N/A
Plant: TBD

Instrument
UPLC-MRM/MS
Chemical Class

Nucleotide synthesis precursors,
intermediates and end products

Metabolic Pathways

Nucleotide synthesis,
IMP synthesis,
UMP synthesis

Compounds

 

Name HMDB ID Super Class Class
5-aminoimidazole ribonucleotide (ribotide) (AIR)      
5-aminoimidazole-4-Carboxamide Riboside (AICAR)      
5-Formylamino-4-imidazolecarboxamide Ribonucleotide (FAICAR)      
Carbamoyl aspartate      
Carbamoyl phosphate      
Carboxyaminoimidazole ribonucleotide (CAIR)      
Dihydrorotate      
Formylglycinamide Ribotide (FGAR)      
Formylglycinamidine Ribotide (FGAM)      
Glycinamide ribonucleotide (GAR)      
N-Succinyl-5-aminoimidazole-4-carboxamide (SAICA)      
N-Succinyl-5-aminoimidazole-4-carboxamide Riboside (SAICAR)      
Orotidine-5P      
Phosphoribosyl amine      
IMP HMDB00175 Nucleosides, nucleotides, and analogues Purine nucleotides
UMP HMDB00288 Nucleosides, nucleotides, and analogues Pyrimidine nucleotides
Phosphoribosyl pyrophosphate (PRPP)   Organic oxygen compounds Organooxygen compounds
Ribose-5P   Organic oxygen compounds Organooxygen compounds
Orotate   Organoheterocyclic compounds Diazines

We request that any publications, posters, or oral presentations resulting from work performed by The Metabolomics Innovation Centre acknowledge TMIC. This allows the Centre to report information such as impact on Canadian researchers to our funding agencies. Clients should also keep us apprised of any publications, posters, or oral presentations arising from work performed at TMIC.

Cutting edge services for metabolomics analysis, including targeted/quantitative analyses, global metabolomic analyses, and bioinformatics support.
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